Please read full Prescribing Information for NUPLAZID, including Boxed WARNING.

Please read full Prescribing
Information
for NUPLAZID®, including Boxed WARNING.

helping you or your loved one start and stay on NUPLAZID® (pimavanserin).

Learn about insurance coverage, financial support options, and where you can find additional support.

financial support options for any insurance situation:

Acadia Connect® provides insurance support services to help you or your loved one understand and navigate the insurance coverage process for NUPLAZID.

Government Insurance (Medicare/Medicaid)

Coverage

100%

of Medicare Part D plans

Commercial Insurance

Copay Program

$0

copay for eligible patients

Through the Acadia Connect® Commercial Copay Program, eligible commercially insured patients may pay as little as $0 per month.*

*Terms, conditions, and program maximums apply. This program is not open to patients receiving prescription reimbursement under any federal, state, or government-funded healthcare program. Not valid where prohibited by law.

what to know about Medicare Part D:

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$2,100 annual cap on out-of-pocket costs

In 2026, Medicare Part D limits your out-of-pocket prescription drug costs to $2,100 for the year. Once you reach that cap, you pay nothing more for covered drugs—including NUPLAZID—for the rest of the plan year.

The 2027 Medicare Part D annual out-of-pocket maximum is expected to increase to $2,400.

https://www.medicare.gov/health-drug-plans/part-d

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Spreading out prescription costs

The Medicare Prescription Payment Plan (MPPP) is a free, voluntary program that helps you manage prescription drug costs. Instead of paying larger amounts up front, you can spread smaller monthly payments throughout the year. You can enroll by phone, online, or by paper form through your plan.

https://www.medicare.gov/prescription-payment-plan/before-payment-option

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Extra Help for prescription costs

You may qualify for Extra Help—a Medicare program that reduces or eliminates your Part D premiums, deductibles, and copays. In 2026, income limits are approximately $23,475 for an individual†‡ and $31,725 for a two-person household.†‡

The 2027 Medicare Part D annual income limits are expected to increase to $23,490 for an individual†‡ and $32,460 for a two-person household.†‡

†Subject to change.

‡These income limits are higher in Alaska and Hawaii.

https://www.medicare.gov/extrahelp

other resources available to you:

Available Nationally and in Your Area
Organization NameContact InformationServices Offered
CMS Medicare Plan Finderwww.medicare.gov/plan-compareCompare Medicare drug plans, find coverage options, and estimate out-of-pocket costs.
Medicare Navigatorsthemedicarenavigators.com1-810-740-2010Free counseling on Medicare plan options, appeals, and enrollment. Available through SHIP (State Health Insurance-Assistance Programs).
State Health Insurance Assistance Program (SHIP)shiphelp.org1-877-839-2675In-depth, one-on-one insurance counseling and assistance with Medicare.

independent charitable foundations (ICFs).§

Acadia Connect® can provide information about third-party ICFs that may be able to help patients with various forms of assistance, including out-of-pocket costs.

Financial Assistance Foundations

Organization NameOrganization WebsiteParkinson's Specific WebsitePhone NumberHours
HealthWell Foundationhealthwellfoundation.orghttps://www.healthwellfoundation.org/fund/neurocognitive-disease-with-psychosis-medicare-access/1-800-675-8416Monday-Friday, 9:00 AM to 5:00 PM ET
Patient Advocate Foundation
TotalAssist
totalassist.orghttps://totalassist.org/funds/parkinsons-disease/1-866-512-3861Monday-Friday, 8:30 AM to 5:30 PM ET
The Assistance Fundtafcares.orghttps://enroll.tafcares.org1-855-845-3663Monday-Friday, 9:00 AM to 5:30 PM ET

§These ICFs are not affiliated with Acadia Pharmaceuticals. Foundation availability and eligibility are subject to change. Acadia cannot guarantee that a patient will receive assistance.

check out this video to see how we work:

See how Acadia Connect® Care Coordinators work to help you navigate the complex insurance landscape, coordinate with your pharmacy to get your prescription, and provide support and education along the way.

get started with support for your NUPLAZID treatment journey.

Fill out and submit the online enrollment form today to join Acadia Connect®.

Enroll Now

Connect with us

1-844-737-2223

Mon-Fri, 8:00 AM to 8:00 PM ET

Important Safety Information and Indication for NUPLAZID® (pimavanserin)

Indication

NUPLAZID is a prescription medicine used to treat hallucinations and delusions associated with Parkinson’s disease psychosis.

Important Safety Information

What is the most important information I should know about NUPLAZID?

  • Medicines like NUPLAZID can raise the risk of death in elderly people who have lost touch with reality (psychosis) due to confusion and memory loss (dementia).
  • NUPLAZID is not approved for the treatment of patients with dementia who experience psychosis unless their hallucinations and delusions are related to Parkinson’s disease.

Who should not take NUPLAZID?

  • Do not take NUPLAZID if you have had an allergic reaction to any of the ingredients in NUPLAZID. Allergic reactions have included rash, hives, swelling of the tongue, mouth, lips, or face, throat tightness, and shortness of breath.
  • Do not take NUPLAZID if you have certain heart conditions that change your heart rhythm. It is important to talk to your healthcare provider about this possible side effect. Call your healthcare provider if you feel a change in your heartbeat.

What other warnings should I know about NUPLAZID?

  • QT Interval Prolongation: NUPLAZID may increase the risk of changes to your heart rhythm. This risk may increase if NUPLAZID is taken with certain other medications known to prolong the QT interval. Tell your healthcare provider about all the medicines you take or have recently taken.

Please also see What is the most important information I should know about NUPLAZID?

What medicine might interact with NUPLAZID?

  • Tell your healthcare provider about all the medicines you take. Other medicines may affect how NUPLAZID works. Some medicines should not be taken with NUPLAZID. Your healthcare provider can tell you if it is safe to take NUPLAZID with your other medicines. Do not start or stop any medicines while taking NUPLAZID without talking to your healthcare provider first.

What are the common side effects of NUPLAZID?

  • The common side effects of NUPLAZID include swelling in the legs or arms, nausea, confusion, hallucination, constipation, and changes to normal walking. These are not all the possible side effects of NUPLAZID. For more information, ask your healthcare provider about this medicine.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1–800–FDA–1088. You can also call Acadia Pharmaceuticals Inc. at 1–844–4ACADIA (1–844–422–2342).

Please read the full Prescribing Information, including Boxed WARNING, also available at NUPLAZID.com.

How should I take NUPLAZID?

The recommended dose of NUPLAZID is one 34 mg capsule once per day, taken by mouth, with or without food.

NUPLAZID is available as 34 mg capsules and 10 mg tablets.